OnabotulinumtoxinA (Botox), is made from the bacteria that causes botulism. Botulinum toxin acts as a Neuromuscular Blocker and blocks nerve activity in the muscles. It acts at the neuromuscular junction to cause muscle paralysis by inhibiting the release of acetylcholine from presynaptic motor neurons.
Botox is used in adults to treat cervical dystonia (severe spasms in the neck muscles), or muscle stiffness in the elbows, wrists, fingers, ankles, or toes. Also used in the treatment of Overactive bladder (OAB) symptoms & preventive treatment of migraine.